This page details the history of Pro Labo Holdings (formerly Esthe Pro Labo).
| 2002 | Sep. | Established Esthe Pro Labo as a limited liability company in Aoba-ku, Yokohama. |
| Oct. | Opened the aesthetic salon BlANCHENEIGE in Aoba-ku, Yokohama. | |
| 2005 | Mar. | Signed a consulting agreement to support Aoki Holdings (publicly listed) in entering the aesthetic business. Comprehensively produced Kaikatsu SPA, one of Japan’s largest spa facilities. |
| Oct. | Reorganized into a corporation (capital 10 million yen). | |
| 2006 | Feb. | Increased capital to 20 million yen and launched product development of supplements and cosmetics. |
| June | Relocated the head office to Shiba Daimon, Minato-ku, Tokyo. | |
| 2007 | Aug. | Increased capital to 30 million yen. |
| Sep. | Increased capital to 33 million yen. | |
| 2008 | May | Launched the purpose-specific salon-exclusive blended herbal tea Professional Use Herb Tea Selection. Exhibited for the first time at Beautyworld Japan 2008, one of Japan’s largest international beauty trade shows. |
| Aug. | Exhibited for the first time at the Diet & Beauty Fair 2008. | |
| Sep. | Relocated the head office to Mita, Minato-ku, Tokyo. | |
| 2009 | Oct. | Exhibited for the first time at Beautyworld Japan West 2009 (Osaka). |
| 2011 | Jan. | Became an official supporter (exhibitor) at the 1st Esthetique Grandprix. Launched the Pro Labo Holdings New Year Party. Launched the business plan presentation meeting. |
| Dec. | Relocated the head office to THE ITOYAMA TOWER in Mita, Minato-ku, Tokyo. Opened a training center and showroom. |
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| 2012 | May | Launched HERB ZYME. |
| Nov. | Exhibited for the first time at SPORTEC 2012, Japan’s largest trade show for revitalizing sports and health facilities. | |
| 2013 | Apr. | Launched the Certified Salon System. |
| 2014 | Feb. | Participated in the establishment of the Japan Enzyme & Hydrogen Medical Beauty Association (JEHMB). |
| 2015 | Jan. | Launched the AILE D’ORE SALON System. Launched the 1st Pro Labo Award. |
| Feb. | Established the Osaka Office and Osaka Training Center for Pro Labo Holdings Co., Ltd. | |
| Mar. | Exhibited for the first time at Beautyworld Japan Fukuoka 2015. Established Pro Labo Consulting Co., Ltd., a wholly owned subsidiary. |
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| July | Opened the inner beauty salon Esthe Pro Labo AOYAMA. | |
| Sep. | Co-hosted the 1st Beauty Business Compliance Association (BBCA) with Seiko Noda, a Member of the House of Representatives. Became the official partner of Kunihiko Morinaga’s brand ANREALAGE for the Spring/Summer 2016 Paris Collection. |
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| Nov. | Formed a business alliance with Kyoei Boxing Gym, which has produced 12 world champions. | |
| 2016 | May | Established Pro Labo Concept Co., Ltd., a wholly-owned subsidiary. |
| Sep. | Exhibited at the 23rd Tokyo Girls Collection 2016 AUTUMN/WINTER, one of Japan’s largest fashion events. | |
| Sep. | Formed a partnership with Jean Yip Group, Singapore’s largest beauty group. | |
| 2017 | Feb. | Officially exhibited at the Academy Awards Secret Party in Los Angeles, USA. Formed a partnership with BeautyFarm, a leading beauty and esthetics group in China. |
| Mar. | Opened the inner beauty salon Esthe Pro Labo GINZA. | |
| May | Opened the first Esthe Pro Labo MACAU store at the Legend Palace Hotel in Macau (licensing agreement). Exhibited for the first time at CHINABEAUTY EXPO 2017 in Shanghai, China. |
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| Sep. | Exhibited for the first time at the Guangzhou Beauty Expo 2017 in Guangzhou, China. Opened the second Esthe Pro Labo MACAU store at The Venetian Macao Resort Hotel in Macau (licensing agreement). |
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| Nov. | Opened the inner beauty salon Esthe Pro Labo GINZA II. Exhibited for the first time at Cosmoprof ASIA 2017 in Hong Kong, China. |
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| 2018 | Jan. | Renamed the Japan Enzyme & Hydrogen Medical Beauty Association (JEHMB) to the Inner Beauty Medical Foundation (IBMF). Opened the third Esthe Pro Labo MACAU store at the Galaxy Hotel in Macau (licensing agreement). |
| Feb. | Changed the company name from Esthe Pro Labo Co., Ltd. to Pro Labo Holdings Co., Ltd. and from Pro Labo Consulting Co., Ltd. to Pro Labo Solution Co., Ltd. | |
| Mar. | Opened the inner beauty salon Esthe Pro Labo TENJIN. | |
| June | Hosted the first successful case presentation meeting of the Inner Beauty Medical Foundation (IBMF). | |
| Sep. | Opened the Esthe Pro Labo Official Store on Alibaba Tmall. | |
| Oct. | Established the Vietnam Branch. | |
| Nov. | Opened the Gran Pro Clinic Ginza. | |
| Dec. | Hosted the first general meeting of the Inner Beauty Medical Foundation (IBMF). | |
| 2019 | Feb. | Opened Esthe Pro Labo SHANGHAI at Isetan in Shanghai, China. |
| Apr. | Hosted the Japan-China Women Entrepreneurs Association Forum. | |
| June | Opened the inner beauty salon Esthe Pro Labo NAMBA. | |
| July | Held the first Esthe Pro Labo Customer Appreciation Festival. | |
| Oct. | Launched the Gran Medic brand. | |
| Nov. | Participated in the WEIBO Account Festival in Japan 2019. | |
| Dec. | Opened the inner beauty salon Esthe Pro Labo SHIBUYA. Established the Shanghai Branch. Appointed Kenta Maeda, a Major League Baseball player for the Minnesota Twins, as Esthe Pro Labo brand ambassador. |
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| 2020 | Feb. | Opened the inner beauty salon Esthe Pro Labo ROPPONGI (limited-time only). Joined the Japan Well-Aging Testing Association. |
| Apr. | Hosted a sales growth seminar. | |
| May | Opened the Gran Pro Medical Spa. | |
| June | Opened the Gran Pro Dental Clinic Ginza. Simultaneously launched the official Shopee store in four countries (Taiwan, Singapore, Thailand, Malaysia). |
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| July | Held the first successful case study meeting by Pro Labo Solution Co., Ltd. Established the Fukuoka Office of Pro Labo Holdings Co., Ltd.. |
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| Sep. | Established Pro Labo Farm. | |
| Dec. | Opened the inner beauty salon Esthe Pro Labo KYOTO. Opened a limited-time store inside Hankyu Umeda Main Store. |
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| 2021 | Jan. | Opened a limited-time store in GINZA SIX. Established the AILE D’ORE PREMIUM CLUB. Published the book Branding Strategies to Create a 10 Billion Yen Market. |
| Feb. | Opened a limited-time store in Daimaru Tokyo. Sold Triple Cutter Chocolate for a limited time at Isetan Shinjuku Beauty Apothecary. |
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| Mar. | Opened the inner beauty salon Esthe Pro Labo ROPPONGI. | |
| Apr. | Opened the Gran Pro Medical Spa Omotesando. | |
| June | Opened the inner beauty salon Esthe Pro Labo NAGOYA. | |
| July | Opened the inner beauty sushi restaurant Azabu Kuroshari. Established Pro Labo Vietnam / Vietnam Branch. Established Pro Labo Shanghai in China. |
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| Sep. | Launched the femtech business. Began operating the thermal wellness business INSEA. |
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| Nov. | Opened the inner beauty salon Esthe Pro Labo HAKATA. | |
| 2022 | Jan. | Launched the Gran Move brand. |
| Mar. | Opened the inner beauty salon Esthe Pro Labo UMEDA. Established the Onkatsu Meister® Association. |
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| Apr. | Opened the inner beauty salon Esthe Pro Labo SAPPORO. Opened the restaurant Azabu Nikushari. |
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| June | Started operating the sauna business The Pro Labo Sauna. Established the Onkatsu Meister® Association. |
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| Aug. | Opened the inner beauty salon Esthe Pro Labo SHINSAIBASHI. | |
| Sep. | Opened the inner beauty salon Esthe Pro Labo KOBE. | |
| Nov. | Established Pro Labo Ryukyu Co., Ltd. | |
| 2023 | Jan. | Opened the inner beauty salon Esthe Pro Labo HANEDA TOKYO. |
| Feb. | Opened the inner beauty salon Esthe Pro Labo OKINAWA. | |
| Mar. | Opened a limited-time store in Matsuzakaya Shizuoka. Opened the inner beauty salon Esthe Pro Labo SHINJUKU MINAMIGUCHI. Opened the inner beauty salon Esthe Pro Labo SHINJUKU. Recognized as a 2023 Health & Productivity Management Outstanding Organization (Small and Medium-Sized Enterprise Category). Established the Japan Femtech Meister® Association (FMA). |
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| Apr. | Opened Pro Labo CAFÉ. Opened the Kanucha Pro Labo Spa. |
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| June | Opened the inner beauty salon Esthe Pro Labo TAKASAKI (franchise). | |
| Aug. | Opened the inner beauty salon Esthe Pro Labo ICHINOMIYA (franchise). | |
| Sep. | Opened the inner beauty salon Esthe Pro Labo SHIZUOKA. Launched the Exosome Treatment Marunouchi Salon. |
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| Oct. | Opened the inner beauty salon Esthe Pro Labo NIHONBASHI. | |
| Nov. | Opened the inner beauty salon Esthe Pro Labo AZABUDAI HILLS. Opened the restaurant Shinjuku Kinshari. |
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| Dec. | Opened the inner beauty salon Esthe Pro Labo KAWAGUCHI (franchise). Opened the Reverse Aging Spa R and Secret Lounge L. |
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| 2024 | Apr. | Appointed Yuto Nagatomo, a professional soccer player, as the global ambassador for Protein Natura Gran Pro. Opened the inner beauty salon Esthe Pro Labo PRAGUE inside Andaz Prague in the Czech Republic (licensing agreement). Opened the inner beauty salon Esthe Pro Labo UTSUNOMIYA (franchise). |
| May | Opened the inner beauty salon Esthe Pro Labo NIIGATA (franchise). Aired the TV commercial Karada ni Bravo on TV Asahi (Nippon Television) networks from May 29 to June 6. |
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| July | Opened the inner beauty salon Esthe Pro Labo KUMAMOTO (franchise). | |
| Aug. | Opened the inner beauty salon Esthe Pro Labo SINGAPORE in Takashimaya Singapore (licensing agreement). | |
| Oct. | Launched the sleep beauty business, leveraging WOTT technology to approach high-quality sleep. Opened the sleep beauty support salon NEMURY (Nemury). Started the employee benefits business. Established the Pro Labo Wellness Club (PWC), a corporate partner program to support company employees. |